Proliferative enteropathy of horses

Document Type : Original Articles

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Abstract

Proliferative enteropathy (PE) is a recently described disease of horses that is char­ acterized by signs of elevated body temperature, weight loss, diarrhea and death. The disease is caused by Lawsonia intracellularis. n-eatment may include jlunixin meglu­ mine,dexamethasone and prednisone to control inflammation. In addition antiulcer drugs such as cimetidine may be required. Finally, antibiotic therapy such as oral ad­ ministration of combined erythromycin/rifampin, or chloramphenicaol and oxytetracy­ cline should be initiated.When PE was described in horses for the first time, Campylobacter spp was thought to be the causative agent (Duhamel and. Wheel­ don 1982). However when the second equine case was reported, the causative agent, Law­ sonia intracellularis, has been well character­ ized in pigs

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