ALTERATIONS IN SOME BIOCHEMICAL PARAMETERS IN CATTLE AFFECTED WITH FOOT AND MOUTH DISEASE IN DAKAHLIA GOVERNORATE, EGYPT

Authors

1 Animal Health Research Institute, Mansoura Provincial Laboratory, Mansoura, Egypt.

2 Department of Biochemistry, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt

3 Department of Physiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.

Abstract

This study was carried out to evaluate the changes in serum biochemical parameters during foot and mouth disease (FMD) viral infection, so blood samples were collected from different farms in Dakahlia Governorate during the outbreak of the disease in 2016. Blood samples were collected after complete clinical and physical examination of twenty five cattle; their ages were ranging from 1-2 years and divided into two groups as follows: 15 cattle were showing the clinical signs of the disease and 10 cattle were clinically healthy (control group). The obtained results showed a significant increase in glucose level (P<0.01), non-esterified fatty acids (NEFA) (P<0.001), beta hydroxyl butyric acid (BHBA) (P<0.001) and lipase enzyme (P<0.01) in infected cattle compared to control group. On the other hand, serum insulin concentration and amylase were significantly lower in blood of infected cattle than control group (P<0.001) and (p < 0.01) respectively. from the obtained results it could be concluded that FMD infection in cattle is associated with hyperglycemia, hypoinsulinemia and ketosis.

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