Pathological, biochemicaLl and toxicojogical studies on metronidazole drug in goats

The study aims to be drug metronidazole ( Filagel ) is used as an antibiotic against parasites anaerobic unicellular against bacteria, anaerobic gram-negative and used in the field of veterinary medicine for the prevention and treatment of disease coccidiosis chickens and animals against the disease trichomoniasis in dogs against diseases of bacterial anaerobic different , and the aim of this study try to use this drug intravenously in goats Egyptian doses ( therapeutic dose and weaknesses ) , guided dose prescribed for humans per kg of weight , and Lhz purpose was divided 15 male goats apparently healthy to one of private farms into 3 equal groups , the first group intact and used as an officer ’s experience . The second group was injected with a dose of 25 mg / kg body weight intravenously . And the third group was injected with 50 mg / kg body weight . Were intravenous injection of two once daily for five consecutive days on the sixth day were slaughtered Ahiwanat whole blood samples were taken for testing Alheimatulogih , and samples of serum to work testing the biochemical and immunological , and samples of the liver and the whole spleen to study changes Alheistobathologih associated with injection drug. Based on the results of the study it was concluded that injection drug in goats by 50 mg / kg of the weight of the neighborhood latest anemia goats ( because of a shortage of moral in the number of blood cells Hamra and Al Beida and platelets and a lack of hemoglobin concentration ) , and Ahddt inhibition immunoprecipitation ( due to the increase in immune cartons serum and changes in solubility the pipeline kidneys ) , but this is recommended work another study to study the monuments previous week in goats after giving a dose of 25 mg / kg body weight intravenously and by drinking to know whether the changes which have taken place in this dose is the changes are temporary and the mirror is normal or not, and so before using this drug dose in the original goats .