Preliminary trials for production of trivalent inactivated oil vaccine against newcastle, infectious bronchitis and egg drop syndrome diseases

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Newcastle disease virus (NDV), egg drop syndrome (EDS) and infectious bronchitis (IBV) combined trivalent and monovalent oil adjuvant vaccines were prepared and tested for safety and immunogenicity in 4 week-old commercial chickens. The chickens vaccinated with a dose of 0.5 ml developed satisfactory levels of antibodies to ND. EDS and IB viruses. The results showed that no significant differences in antibody titres between the respective groups up to 8 week observation period. So, the trivalent vaccine was safe and immunogenic against NDV, EDSV and IBV in one dose.

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