TY - JOUR ID - 205846 TI - Comparative effect of probiotic and/or canola seed, canola meal and canola oil dietary supplementation on growth performance, blood component, antioxidant status and immune response in growing rabbits. JO - Mansoura Veterinary Medical Journal JA - MVMJ LA - en SN - 1110-7219 AU - Al-Rakhawi, Merna AU - M. A. Abo El-Maaty, Hayam AU - Risha, Engy AU - Abdelhamid, Fatma AD - Department of Clinical Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura,35516, Egypt AD - Department of Poultry Production, Faculty of Agriculture, Mansoura University, Mansoura, Egypt, Mansoura University, Mansoura, Egypt AD - Department of Clinical pathology, Faculty of Veterinary Medicine , Mansoura University, Mansoura 35516, Egypt AD - Department of Clinical Pathology, Faculty of Veterinary Medicine Mansoura University Y1 - 2021 PY - 2021 VL - IS - SP - EP - KW - ProgutĀ® KW - canola KW - Rabbit KW - Immune Response KW - antioxidant status DO - 10.21608/mvmj.2021.79480.1063 N2 - Objective: This study was performed to investigate the effect of probiotic and/or canola seed, canola meal, and canola oil on growth performance, blood component, antioxidant status, and immune response of growing rabbits. Design: Randomized -controlled experimental study.Animals: One hundred and twenty mixed-sex California rabbits.Procedures: Rabbits used for this study were randomly assigned into 8 equal groups: the control non supplemented group and the other supplementd groups including, probiotic - ProgutĀ® (PG) (1.0g/kg), canola seed (CS) (15%), canola seed + probiotic (CS+PG), canola meal (CM) (15%), canola meal + probiotic (CM+PG), canola oil (CO) (1.5%), and canola oil + probiotic (CO+PG). Growth performance, liver and kidney function biomarkers, lipid profile, oxidative stress, and antioxidant markers as well immunological parameters were determined at the end of the study.Results:. CM and CO showed the strongest impact on the growth performance as they significantly increased body weight gain and reduced feed intake (p < 0.05). PG supplementation significantly increased IgM and nitric oxide levels and decreased blood cholesterol (p < 0.05). CS and CM supplementation significantly raised leukocytic count, total protein, and globulin level (p < 0.05). Additionally CS increased serum lysozyme activity while CM increased hepatic GSH level. CO highly increased (p < 0.05) the values of total protein, globulin, SOD, GSH, as well lysozyme and significantly diminished MDA. Conclusion and clinical relevance: Supplementation of CS with probiotic for growing rabbits is recommended to obtain great outcome on general animal health, immunity, and performance without adverse effect on lipogram. UR - https://mvmj.journals.ekb.eg/article_205846.html L1 - ER -